News: Structural variants characterized in the human genomeJuly 18, 2019 2023-04-02 1:45
Structural variants characterized in the human genome
The human genome differs from person to person. In the DNA sequence, for example, individual "letters", so-called nucleotides, are altered. Even greater differences result from structural variants that arise when large DNA segments are inserted, deleted or moved. As part of a global team of researchers, bioinformaticians at Saarland University have studied these differences in more detail and comprehensively characterized the structural variants in three families. The scientists have thus created a basis for systematically exploring the consequences of these genetic variants. The results have been published in Nature Communications.