{"id":6690,"date":"2019-07-18T09:07:00","date_gmt":"2019-07-18T07:07:00","guid":{"rendered":"https:\/\/zbi-dev.cs.uni-saarland.de\/?p=6690"},"modified":"2023-04-02T01:45:21","modified_gmt":"2023-04-01T23:45:21","slug":"structural-variants-characterized-in-the-human-genome","status":"publish","type":"post","link":"https:\/\/zbi-dev.cs.uni-saarland.de\/en\/structural-variants-characterized-in-the-human-genome\/","title":{"rendered":"Structural variants characterized in the human genome"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"6690\" class=\"elementor elementor-6690\">\n\t\t\t\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-52c4e0c elementor-section-boxed elementor-section-gap-beside-yes elementor-section-height-default elementor-section-height-default elementor-section-column-vertical-align-stretch\" data-id=\"52c4e0c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-155b728\" data-id=\"155b728\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-306f13c elementor-widget elementor-widget-ekit_wb_6392\" data-id=\"306f13c\" data-element_type=\"widget\" data-widget_type=\"ekit_wb_6392.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"news-custom-widget news-excerpt-widget\" data-translated=\"yes\" data-date=\"2019-04-17\" data-source=\"sic\" data-title=\"Strukturvarianten im menschlichen Genom systematisch charakterisiert\" data-custom=\"\">\n    <div class=\"news-excerpt-content\">\n        <p>The human genome differs from person to person. In the DNA sequence, for example, individual \"letters\", so-called nucleotides, are altered. Even greater differences result from structural variants that arise when large DNA segments are inserted, deleted or moved. As part of a global team of researchers, bioinformaticians at Saarland University have studied these differences in more detail and comprehensively characterized the structural variants in three families. The scientists have thus created a basis for systematically exploring the consequences of these genetic variants. The results have been published in Nature Communications.<\/p>    <\/div>\n    <div class=\"news-excerpt-info\">This (and the button text) will be formatted automatically depending on title, source, date, and the page's language.<\/div>\n    <div class=\"news-custom-widget-button-wrapper\">\n        <a class=\"news-custom-widget-button\" href=\"https:\/\/saarland-informatics-campus.de\/piece-of-news\/strukturvarianten-im-menschlichen-genom-systematisch-charakterisiert\/\" rel=\"nofollow\" target=\"_blank\">\n            <span class=\"news-excerpt-button-label\">Read article<\/span>\n            <i class=\"icon icon-right-arrow\"><\/i>\n        <\/a>\n    <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a71e60a elementor-section-boxed elementor-section-gap-beside-yes elementor-section-height-default elementor-section-height-default elementor-section-column-vertical-align-stretch\" data-id=\"a71e60a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-08253cd\" data-id=\"08253cd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-34b03e2 elementor-widget elementor-widget-spacer\" data-id=\"34b03e2\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.14.0 - 26-06-2023 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e9d5736 elementor-section-boxed elementor-section-gap-beside-yes elementor-section-height-default elementor-section-height-default elementor-section-column-vertical-align-stretch\" data-id=\"e9d5736\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fe53edf\" data-id=\"fe53edf\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6b1841d elementor-widget elementor-widget-ekit_wb_6533\" data-id=\"6b1841d\" data-element_type=\"widget\" data-widget_type=\"ekit_wb_6533.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"news-custom-widget news-related-publication-widget\" data-heading=\"yes\" data-plural=\"\" data-journal=\"nature communications\" data-doi=\"10.1038\/s41467-018-08148-z\" data-authors=\"\" data-title=\"Multi-platform discovery of haplotype-resolved structural variation in human genomes\" data-year=\"2019\">\n    <h4 class=\"news-related-publication-header\">Related Publication<\/h4>\n    <div class=\"news-related-publication-content\">. (2019). \"Multi-platform discovery of haplotype-resolved structural variation in human genomes\". nature communications. DOI:10.1038\/s41467-018-08148-z.\n    <\/div>\n    <div class=\"news-custom-widget-button-wrapper\">\n        <a class=\"news-custom-widget-button\" href=\"https:\/\/www.nature.com\/articles\/s41467-018-08148-z\" rel=\"nofollow\" target=\"_blank\">\n            <span class=\"news-related-publication-button-label\">Read publication<\/span>\n            <i class=\"icon icon-right-arrow\"><\/i>\n        <\/a>\n    <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>The human genome differs from person to person. In the DNA sequence, for example, individual &#8220;letters&#8221;, so-called nucleotides, are altered. Even greater differences result from structural variants that arise when large DNA segments are inserted, deleted or moved. As part of a global team of researchers, bioinformaticians at Saarland University have studied these differences in more detail and comprehensively characterized the structural variants in three families. The scientists have thus created a basis for systematically exploring the consequences of these genetic variants. The results have been published in Nature Communications.<\/p>\n","protected":false},"author":5,"featured_media":6685,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[498,608,476],"tags":[618],"acf":[],"_links":{"self":[{"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/posts\/6690"}],"collection":[{"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/comments?post=6690"}],"version-history":[{"count":4,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/posts\/6690\/revisions"}],"predecessor-version":[{"id":6694,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/posts\/6690\/revisions\/6694"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/media\/6685"}],"wp:attachment":[{"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/media?parent=6690"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/categories?post=6690"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zbi-dev.cs.uni-saarland.de\/wp-json\/wp\/v2\/tags?post=6690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}