Welcome to the Chair for Bioinformatics!

Our research group develops bioinformatics methods and software for the elucidation of pathogenic processes and for the diagnosis, prognosis, and therapy of diseases.

Study of
Pathogenic
Processes

Diagnosis
and
Prognosis
Therapy

Bioinformatics
Methods and
Software

Recent Publications

Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing

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Nature Communications (August 7, 2023)

Time-resolved RNA signatures of CD4+ T cells in Parkinson’s disease

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Cell Death Discovery (January 21, 2023)

Changes of Protein Expression after CRISPR/Cas9 Knockout of miRNA-142 in Cell Lines Derived from Diffuse Large B-Cell Lymphoma

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Cancers (October 14, 2022)

Simultaneous regression and classification for drug sensitivity prediction using an advanced random forest method

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Scientific Reports (August 5, 2022)

The DGCR8 E518K mutation found in Wilms tumors leads to a partial miRNA processing defect that alters gene expression patterns and biological processes

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Oxford Academic Carcinogenesis (February 1, 2022)

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

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Nature Communications (January 12, 2022)

GeneTrail: A Framework for the Analysis of High-Throughput Profiles

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Frontiers in Molecular Biosciences (September 16, 2021)

MERIDA: a novel Boolean logic-based integer linear program for personalized cancer therapy

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Bioinformatics (September 5, 2021)

miRTargetLink 2.0—interactive miRNA target gene and target pathway networks

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Nucleic Acids Research (May 1, 2021)

Validation of human microRNA target pathways enables evaluation of target prediction tools

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Nucleic Acids Research (January 11, 2021)