Welcome to the Chair for Bioinformatics!

Welcome to the Chair for Bioinformatics!

Our research group develops bioinformatics methods and software for the elucidation of pathogenic processes and for the diagnosis, prognosis, and therapy of diseases.

Recent Publications

Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing

Time-resolved RNA signatures of CD4+ T cells in Parkinson’s disease

Changes of Protein Expression after CRISPR/Cas9 Knockout of miRNA-142 in Cell Lines Derived from Diffuse Large B-Cell Lymphoma

Simultaneous regression and classification for drug sensitivity prediction using an advanced random forest method

The DGCR8 E518K mutation found in Wilms tumors leads to a partial miRNA processing defect that alters gene expression patterns and biological processes

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

GeneTrail: A Framework for the Analysis of High-Throughput Profiles

MERIDA: a novel Boolean logic-based integer linear program for personalized cancer therapy

miRTargetLink 2.0—interactive miRNA target gene and target pathway networks

Validation of human microRNA target pathways enables evaluation of target prediction tools