Research
January 18, 2012 2023-11-15 16:03Research
Our research group develops bioinformatics methods and software for the elucidation of pathogenic processes and for the diagnosis, prognosis, and therapy of diseases.
![IMG_9081 Slide](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
Pathogenic
Processes
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
and
Prognosis
Therapy
Methods and
Software
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
Publications
The researchers in our group regularly publish projects, studies and findings in renowned scientific journals.
Former Projects
Here, we present a list of our former projects. Please visit the given links for more information about the respective projects.
![BALL_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/ball.png)
BALL
The Biochemical Algorithms Library (BALL) is a C++ framework for rapid software prototyping in Computational Molecular Biology and Molecular Modeling.
![BN++_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/bn.png)
BN++
The Biochemical Network library (BN++) is a comprehensive framework for modeling, analyzing, and visualizing biochemical pathways and networks.
![CAP_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/cap.png)
CAP
The 'Cancer-Associated Proteins' database (CAP) is an integrated tool for analysing proteins that show an altered expression in certain tumor types.
![Docking_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/docking.png)
Docking
The main goal of this project is the development of algorithms for predicting the 3D-structures of protein-protein complexes.
![DrugTargetInspector](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2023/04/DrugTargetInspector-73x72.png)
DTI
DrugTargetInspector is an interactive assitance tool for patient treatment stratification.
![GeneTrail_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/genetrail.png)
GeneTrail
We are developing a web-based application, called GeneTrail, that facilitates the statistical evaluation of comprehensive genomic and proteomic data sets with respect to the enrichment of biological categories.
![MolecularDiagnosis_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/moleculardiagnosis.png)
Molecular Diagnosis
Sets of autologous antigen possess high potential for non invasive molecular diagnosis and monitoring. We are developing a statistical framework to perform an accurate diagnosis of various diseases based on autoantibody profiles.
![Solvation_Logo](https://zbi-www.bioinf.uni-sb.de/wp-content/uploads/2012/01/solvation_0.png)
Solvation
Since most biochemical processes require the presence of water, solvation effects play a major role that have to be modelled correctly in order to achieved reliable and meaningful binding energy and docking predictions. Therefore, we are developing improved continuum models for solvation.