Personalized Therapy
October 6, 2023 2023-11-10 11:17Personalized Therapy
![zellen Slide](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
Cancer is a heterogeneous
class of diseases.
The picture on the right
shows the differences
between two breast cancers
(blue and grey)
wrt cancer driver mutations
and the activities of cancer-associated processes.
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
Even cancers of the same
(sub)type differ strongly
wrt their geno- and
phenotype.
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
![zellen Slide](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
Due to cancer heterogeneity,
each tumor/patient requires
a personalized therapy.
However, the challenge is
to identify
the best anti-cancer drug
or drug combination
for a given cancer.
The good news is that more
than 200 anti-cancer drugs
are available today.
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
![zellen Slide](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
We develop
novel approaches
for supporting
tumor therapy optimization.
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)
In particular, we develop
novel AI/ML methods
for the prediction of
effective therapies.
![](https://zbi-www.bioinf.uni-sb.de/wp-content/plugins/revslider/public/assets/assets/dummy.png)